ea0011p495 | Endocrine tumours and neoplasia | ECE2006
Krawczyk A
, Hasse-Lazar K
, Pawlaczek A
, Rusinek D
, Szpak-Ulczok S
, Peczkowska M
, Preibisz A
, Kubaszek A
, Gubala E
, Januszewicz A
, Jarzab B
Tumors derived from chromaffine tissue include pheochromocytomas (tumors located in adrenal medulla) and paragangliomas (extraadrenal tumors). These tumors are in 2025% inherited. Paragangliomas are even rarer and are presented either as familial disease or pheochromocytoma-paraganglioma syndrome (PPS). The mutations in SDH genes (SDHB, SDHD) are suspected for causing the syndrome.The aim of present study is to look for germline mutat...